MalariaChallenge

The MalariaChallenge intervention class is a node-level intervention similar to parameter-campaign-node-outbreak. However, instead of distributing infections, it distributes malaria challenges by either tracking numbers of sporozoites or infectious mosquito bites.

Whether each individual actually becomes infected from the challenge is modified by individual-level factors. Each person's probability of infection is scaled by a combined relative risk that accounts for: * Acquisition immunity -- both naturally acquired immunity that develops over time through repeated exposure and any reduction from acquisition-blocking vaccines (e.g., SimpleVaccine with Vaccine_Type set to AcquisitionBlocking). * Age-dependent biting risk -- if Age_Dependent_Biting_Risk_Type is enabled in the configuration, younger (smaller) individuals receive proportionally fewer bites. * Demographics-based risk -- if Enable_Demographics_Risk is enabled, each individual's personal risk factor from the demographics file further scales their exposure.

Vector control interventions will not affect the infections delivered by this intervention.

If vectors are included when this class is implemented, this will add the infections specified for that month or day in addition to the infections provided by the vectors. Note that the Daily EIR channel in the software-report-inset-chart will not be impacted by this intervention.

Note

Parameters are case-sensitive. For Boolean parameters, set to 1 for true or 0 for false. Minimum, maximum, or default values of "NA" indicate that those values are not applicable for that parameter.

EMOD does not use true defaults; that is, if the dependency relationships indicate that a parameter is required, you must supply a value for it. However, many of the tools used to work with EMOD will use the default values provided below.

JSON format does not permit comments, but you can add "dummy" parameters to add contextual information to your files. Any keys that are not EMOD parameter names will be ignored by the model.

The table below describes all possible parameters with which this class can be configured. The JSON example that follows shows one potential configuration.

Parameter	Type	Min	Max	Default	Description
Challenge_Type	enum	NA	NA	NA	The type of malaria challenge. Possible values are: InfectiousBites If this value is selected, use with the corresponding Infectious_Bite_Count parameter. Sporozoites If this value is selected, use with the corresponding Sporozoite_Count parameter.
Coverage	float	0	1	1	The fraction of individuals receiving an intervention.
Disqualifying_Properties	array of strings	NA	NA	[]	A list of IndividualProperty key:value pairs that cause an intervention to be aborted (persistent interventions will stop being distributed to individuals with these values). See IndividualProperties and NodeProperties parameters for more information. Generally used to control the flow of health care access. For example, to prevent the same individual from accessing health care via two different routes at the same time.
Dont_Allow_Duplicates	bool	NA	NA	0	If set to true (1), does not allow any new interventions with matching Intervention_Name parameter value to be distributed to the individual.
Infectious_Bite_Count	integer	0	1000	1	The number of infectious bites per person. Use when Challenge_Type is set to InfectiousBites.
Intervention_Name	string	NA	NA	MalariaChallenge	The optional name used to refer to this intervention as a means to differentiate it from others that use the same class.
New_Property_Value	string	NA	NA	""	An optional NodeProperty key:value pair that will be assigned when the intervention is applied. See IndividualProperties and NodeProperties parameters for more information.
Sporozoite_Count	integer	0	1000	1	The number of sporozoites per person. Use when Challenge_Type is set to Sporozoites.

{
    "Use_Defaults": 1,
    "Events": [
        {
            "class": "CampaignEvent",
            "Nodeset_Config": {
                "class": "NodeSetAll"
            },
            "Start_Day": 40,
            "Event_Coordinator_Config": {
                "class": "StandardInterventionDistributionEventCoordinator",
                "Intervention_Config": {
                    "class": "MalariaChallenge",
                    "Challenge_Type": "InfectiousBites",
                    "Coverage": 1.0,
                    "Infectious_Bite_Count": 2,
                    "Sporozoite_Count": 3
                }
            }
        }
    ]
}